产品货号：
Z36008
中文名称：
PDGFR alpha/PDGFRA抗体
英文名称：
Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12) |
| 指标别名 | platelet derived growth factor receptor alpha;CD140A;PDGFR-2;PDGFR2;PDGFRA |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | PDGFRA |
| 克隆号 | OTI2B12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 32-324 of human PDGFRA (NP_006197) produced in E.coli. |
| 实际分子量 | 120.3KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | PDGFRA(Platelet-derived growth factor receptor,alpha),also called PDGFR2,encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family.The PDGFA gene is mapped on 4q12.The PDGFRA-FIP1L1 gene is a constitutively activated tyrosine kinase that transforms hematopoietic cells and is a therapeutic target of imatinib.The PDGFRA gene contains 23 exons spanning about 65kb.Using the human PDGFRA promoter linked to a luciferase reporter,Joosten et al.showed that PAX1 acts as a transcriptional activator of the PDGFRA gene in differentiated human embryonal carcinoma cells.PDGFRA is responsible for mediating cellular contraction of multiple growth factors:TGFB1 and members of the PDGF family.Lei et al.noted that in the rabbit model of the disease,PDGFRA is dramatically more capable of promoting PVR than is the closely related PDGFRB.PDGFRA is a critical receptor required for human CMV infection,and thus a target for novel antiviral therapies. |
| Uniprot ID | P16234 |
| 基因名全称 | Platelet-derived growth factor receptor alpha |
| 蛋白名全称 | Platelet-derived growth factor receptor alpha |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：PDGFR alpha/PDGFRA抗体，PDGFR alpha抗体，PDGFRA单抗，Anti-PDGFR alpha/PDGFRA Antibody (Clone#OTI2B12)